ADAPTATION OF FOOT & MOUTH DISEASE VIRUS SUBTYPES PAN ASIA-II, TUR-06 AND SINDH-08 TOWARDS THE VACCINE DEVELOPMENT AND SEROLOGICAL FINDINGS BY SPC ELISA AND SERUM NEUTRALIZATION TEST

نویسندگان

چکیده

FMD serotype “O” with subtype PAN Asia-II, “A” Tur-06 and “Asia-1” Sindh-08 were adapted on the LFBK cell line subsequently BHK-21. After inactivation these subtypes introduced for development of oil based trivalent vaccine against FMD. The study was conducted experimental animals (cow calves) at Livestock Production Research Institute (LPRI), Okara. Twenty one unvaccinated cattle calves age group 4-6 month used in study, 16 injected experimentally prepared dose rate 2cc per cow calf day 0 28 post priming while five kept as control. containing ASIA-II, TUR-06 SINDH-08 showed satisfactory immune response ELISA Serum Neutralization Test (SNT) booster. aimed to strengthen national control strategy by incorporation prevalent field strains virus development.

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ژورنال

عنوان ژورنال: Pakistan journal of science

سال: 2023

ISSN: ['0030-9877', '2411-0930']

DOI: https://doi.org/10.57041/pjs.v72i3.309